ZIA CP010168-10039 (ZIA) | |||
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Title | Maternal and Umbilical Cord Hormone Concentrations in Monochorionic and Dichorion | ||
Institution | NCI, Bethesda, Ma | ||
Principal Investigator | Troisi, Rebecca | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $19,097 | Project Dates | 01/01/2004 - N/A |
Fiscal Year | 2011 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Biochemical Epidemiology (45.0%) Cancer (100.0%) |
Breast (80.0%) Prostate (10.0%) Testes (10.0%) |
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Research Type | |||
Cancer Related Biology Endogenous Factors in the Origin and Cause of Cancer |
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Abstract | |||
The proposed study involves collecting maternal and cord blood samples from monochorionic twin, dichorionic twin and singleton pregnancies of similar gestational age to quantify differences in concentrations of several hormones and other pregnancy products including estriol, estradiol, estrone, testosterone, androstenedione, dehydroepiandrosterone (DHEA), DHEA-sulfate, progesterone, AFP, prolactin, IGF and IGF-binding protein 3. Data from medical records and pathology reports will be abstracted to provide information on the mother, baby, pregnancy and placenta. The work will be done at Dartmouth Hitchcock Medical Center, Dartmouth Medical School. Blood samples labeled with a unique ID number only will be sent to Bioreliance, NCI's contractor, for preperation and shipment to the laboratory that will perform the hormone assays. NCI will receive the abstracted data in electronic form. no personal identifying information will be received by NCI or its contractor. The study has been approved by Dartmouth Medical School. |